Brand Name: Reduce, Reductil, Meridia
Generic Name: Sibutramine HCI
Reduce works by acting on the appetite control centre in the brain. Studies have shown that using Reductil, along with a calorie controlled diet and exercise, helped patients lose weight and maintain weight loss for up to 2 years.
The active ingredient in Reduce, Sibutramine, works in the area of the brain that signals the sense of fullness (satiety). Meridia – the name under which Reduce is marketed in the US – does not suppress appetite, which is your signal to start eating – most people think that it’s an appetite suppressant but actually it just tells your stomach that you are full.
Reduce blocks the re-uptake of the brain chemicals (serotonin and noradrenaline) which help regulate the sense of fullness. Fullness is your signal to stop eating. Having a sense of fullness, or satiety, means you may feel satisfied with less food.
Reduce affects chemicals in the body that are related to weight maintenance.
Reduce is used as a short-term supplement to diet and exercise in the treatment of obesity.